Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1989-11-13
pubmed:abstractText
In 72 episodes of suspected or proven Hickman-catheter-associated infection occurring in 59 patients with various hematological disorders, patients were assigned to treatment with either vancomycin or teicoplanin in a randomized nonblinded prospective study. Of 60 episodes evaluable for response, 28 were treated with vancomycin and 32 were treated with teicoplanin. Sixteen infective episodes were microbiologically documented in the vancomycin group, and twenty-one were microbiologically documented in the teicoplanin group. Microbiologically and clinically documented infections treated with vancomycin had an 80% response rate, compared with a 69% response rate for those treated with teicoplanin (P = 0.316). Adverse events occurred in nine (25%) of the episodes in the vancomycin group, compared with three (8%) in the teicoplanin group (P = 0.044). Teicoplanin may provide an effective alternative to vancomycin in the treatment of Hickman-catheter-associated infection in patients with hematological malignancies.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-109934, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-2888816, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-2949024, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-2962845, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-2965121, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-2965133, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-2965134, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-2965137, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-2968907, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-3155563, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-3337488, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-3337513, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-3526155, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-3526884, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-3945579, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-4030539, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-6103386, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-6219616, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-6239854, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-6360002, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-6377003, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-6394579, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-6440883, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-6850543, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-6988713, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-7103626, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-7125409, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-7143650, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-7268613, http://linkedlifedata.com/resource/pubmed/commentcorrection/2529814-822522
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0066-4804
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1193-7
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Randomized prospective study comparing vancomycin with teicoplanin in the treatment of infections associated with Hickman catheters.
pubmed:affiliation
University Department of Haematology, University of Liverpool, United Kingdom.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial