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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1989-10-31
|
| pubmed:abstractText |
We checked serum beta-endorphin levels in 17 chronic uremic patients under regular hemodialysis and compared them with the levels in 17 age-matched control subjects. Higher levels of serum beta-endorphin were found in uremic patients (22.54 +/- 6.20 pg/0.1 ml vs 9.42 +/- 5.19 pg/0.1 ml, p less than 0.001). There were no sex differences in both uremic patients (M: F = 21.04 +/- 7.53 pg/0.1 ml vs 23.59 +/- 5.25 pg/0.1 ml, p greater than 0.05) and normal control subjects (9.16 +/- 5.15 pg/0.1 ml vs 9.76 +/- 5.55 pg/0.1 ml, p greater than 0.05). No significant difference in the serum levels was noted between the patients with a hemodialysis history longer than two years (19.96 +/- 5.79 pg/0.1 ml vs 25.45 +/- 5.60 pg/0.1 ml, p greater than 0.05) and those with less than a two year's history (19.96 +/- 5.79 pg/0.1 ml vs 25.45 +/- 5.60 pg/0.1 ml, p greater than 0.05). Moreover, serum beta-endorphin levels were not altered after dialysis (22.54 +/- 6.20 pg/0.1 ml to 20.66 +/- 4.57 pg/0.1 ml, p greater than 0.05) by either acetate or bicarbonate dialysate (acetate vs bicarbonate = 20.83 +/- 5.03 pg/0.1 ml vs 20.13 +/- 3.14 pg/0.1 ml, p greater than 0.05). The role of beta-endorphin in the pathogenesis of uremic syndrome still requires further study.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0371-7682
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
88
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
360-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1989
|
| pubmed:articleTitle |
Serum endorphin levels in uremic patients under maintenance hemodialysis.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|