| pubmed-article:2528974 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2528974 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:2528974 | lifeskim:mentions | umls-concept:C1522564 | lld:lifeskim |
| pubmed-article:2528974 | lifeskim:mentions | umls-concept:C0001473 | lld:lifeskim |
| pubmed-article:2528974 | lifeskim:mentions | umls-concept:C0009915 | lld:lifeskim |
| pubmed-article:2528974 | lifeskim:mentions | umls-concept:C0017710 | lld:lifeskim |
| pubmed-article:2528974 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:2528974 | lifeskim:mentions | umls-concept:C0559956 | lld:lifeskim |
| pubmed-article:2528974 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:2528974 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2528974 | pubmed:dateCreated | 1989-11-2 | lld:pubmed |
| pubmed-article:2528974 | pubmed:abstractText | Studies were conducted to examine the effects of chronic adrenalectomy (Adx) and adrenalectomy plus glucocorticoid replacement therapy on rat cardiac contractile protein ATPase activities. The Ca2+-dependent Mg-ATPase activity of myofibrils isolated from rat ventricles 3 weeks postadrenalectomy (Adx) was significantly decreased at all pCa2+ concentrations (P less than 0.01), compared to sham-operated (SO) rats. Similarly, Ca2+-, K+-EDTA, and actin-activated myosin ATPase activities of Adx rat hearts were markedly decreased below that of SO rats (P less than 0.01). Dexamethasone administration to Adx rats prevented the decrease of Ca2+- and K+-ATPase activities of myosin, but not of myofibrillar Ca2+-dependent Mg-ATPase or actin-activated myosin Mg-ATPase activities. These studies suggest that glucocorticoid insufficiency induced by adrenalectomy results in altered myocardial contractile protein ATPase activity which may underlie impaired cardiac performance. | lld:pubmed |
| pubmed-article:2528974 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2528974 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2528974 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2528974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2528974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2528974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2528974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2528974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2528974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2528974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2528974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2528974 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2528974 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:2528974 | pubmed:issn | 0885-4505 | lld:pubmed |
| pubmed-article:2528974 | pubmed:author | pubmed-author:ReddyY SYS | lld:pubmed |
| pubmed-article:2528974 | pubmed:author | pubmed-author:LernerM RMR | lld:pubmed |
| pubmed-article:2528974 | pubmed:author | pubmed-author:StithR DRD | lld:pubmed |
| pubmed-article:2528974 | pubmed:author | pubmed-author:BrackettD JDJ | lld:pubmed |
| pubmed-article:2528974 | pubmed:author | pubmed-author:WilsonM FMF | lld:pubmed |
| pubmed-article:2528974 | pubmed:author | pubmed-author:BhaskarMM | lld:pubmed |
| pubmed-article:2528974 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2528974 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:2528974 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2528974 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2528974 | pubmed:pagination | 118-24 | lld:pubmed |
| pubmed-article:2528974 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:meshHeading | pubmed-meshheading:2528974-... | lld:pubmed |
| pubmed-article:2528974 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2528974 | pubmed:articleTitle | Changes in myocardial contractile protein ATPases in chronically adrenalectomized rats with and without glucocorticoid replacement. | lld:pubmed |
| pubmed-article:2528974 | pubmed:affiliation | Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City. | lld:pubmed |
| pubmed-article:2528974 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2528974 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
