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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1989-10-23
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pubmed:abstractText |
Transcriptional studies of the placental protein Pregnancy Specific beta 1-Glycoprotein (SP1 or PS beta G) gene with a cDNA probe in Northern blot analysis showed 15-20 folds mRNA increase in term placenta compared with early placenta and hydatiform mole. This value parallels the SP1 amount translated in wheat germ cell-free system. We conclude that SP1 biosynthesis is regulated at transcriptional level during placental development and a similar mechanism would occur in hydatiform mole which is a hyperplastic trophoblast tumor.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0158-5231
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
999-1008
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2528957-Bacteriophage lambda,
pubmed-meshheading:2528957-Blotting, Northern,
pubmed-meshheading:2528957-Female,
pubmed-meshheading:2528957-Gene Expression Regulation,
pubmed-meshheading:2528957-Humans,
pubmed-meshheading:2528957-Hydatidiform Mole,
pubmed-meshheading:2528957-Nucleic Acid Hybridization,
pubmed-meshheading:2528957-Placenta,
pubmed-meshheading:2528957-Pregnancy,
pubmed-meshheading:2528957-Pregnancy Proteins,
pubmed-meshheading:2528957-Pregnancy-Specific beta 1-Glycoproteins,
pubmed-meshheading:2528957-Protein Biosynthesis,
pubmed-meshheading:2528957-RNA, Messenger,
pubmed-meshheading:2528957-Transcription, Genetic
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pubmed:year |
1989
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pubmed:articleTitle |
Expression of pregnancy specific beta 1-glycoprotein gene in human placenta and hydatiform mole.
|
pubmed:affiliation |
Departamento de Bioquimica Clinica, Facultad de Ciencias Quimicas, Universidad Nacional de Córdoba.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|