Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1989-8-29
|
pubmed:abstractText |
The insulin secretory granule of the pancreatic B cell is a complex intracellular organelle comprised of a many proteins with different catalytic activities and messenger functions. With the advent of tumour models of the B cells and the application of immunological and molecular cloning techniques considerable progress has been made in recent years towards the elucidation of the structure and function of these granule proteins. A number of examples are selected here for review. Particular emphasis given to how the activities of quite different granule proteins are interdependent and how this contributes to the co-ordination and integration of the organelle's biological functions.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0012-186X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
271-81
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2526768-Amino Acid Sequence,
pubmed-meshheading:2526768-Animals,
pubmed-meshheading:2526768-Cytoplasmic Granules,
pubmed-meshheading:2526768-Humans,
pubmed-meshheading:2526768-Insulin,
pubmed-meshheading:2526768-Islets of Langerhans,
pubmed-meshheading:2526768-Molecular Sequence Data,
pubmed-meshheading:2526768-Proton-Translocating ATPases
|
pubmed:year |
1989
|
pubmed:articleTitle |
The insulin secretory granule.
|
pubmed:affiliation |
Department of Clinical Biochemistry, Addenbrooke's Hospital, Cambridge, UK.
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|