| pubmed-article:2526700 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C0225336 | lld:lifeskim |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C0026473 | lld:lifeskim |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C0040048 | lld:lifeskim |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C0010592 | lld:lifeskim |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C0205184 | lld:lifeskim |
| pubmed-article:2526700 | lifeskim:mentions | umls-concept:C1515895 | lld:lifeskim |
| pubmed-article:2526700 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2526700 | pubmed:dateCreated | 1989-9-1 | lld:pubmed |
| pubmed-article:2526700 | pubmed:abstractText | Monocytes and endothelial cells were stimulated in co-culture with allogeneic lymphocytes to produce thromboplastin (TPL). The induction was biphasic, an early response (8-24 h) was greatly augmented by cyclosporin A (CS) (0.5-5 micrograms/ml) whereas the late response (day 3-4) was inhibited. Prednisolone inhibited both responses. Both drugs inhibited lymphocyte proliferation. Interferon-gamma decreased MLC TPL activity but increased thymidine incorporation. CD4+ cells were instrumental in inducing the early TPL peak in monocytes, whereas CD8+ cells decreased the TPL effect. With endothelial cells both T cell classes were equally effective. Conditioned medium from MLC as well as from co-cultures of endothelial cells and lymphocytes induced early TPL synthesis in endothelial cells. Upon allogeneic stimulation monocytes, but not endothelial cells, produced a significant amount of F-VII, most of which was apparently undercarboxylated. | lld:pubmed |
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| pubmed-article:2526700 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2526700 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2526700 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2526700 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2526700 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:2526700 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:2526700 | pubmed:author | pubmed-author:PrydzHH | lld:pubmed |
| pubmed-article:2526700 | pubmed:author | pubmed-author:GaudernackGG | lld:pubmed |
| pubmed-article:2526700 | pubmed:author | pubmed-author:CarlsenEE | lld:pubmed |
| pubmed-article:2526700 | pubmed:author | pubmed-author:Filion-Mykleb... | lld:pubmed |
| pubmed-article:2526700 | pubmed:author | pubmed-author:PettersenK... | lld:pubmed |
| pubmed-article:2526700 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2526700 | pubmed:volume | 76 | lld:pubmed |
| pubmed-article:2526700 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2526700 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2526700 | pubmed:pagination | 428-33 | lld:pubmed |
| pubmed-article:2526700 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2526700 | pubmed:meshHeading | pubmed-meshheading:2526700-... | lld:pubmed |
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| pubmed-article:2526700 | pubmed:meshHeading | pubmed-meshheading:2526700-... | lld:pubmed |
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| pubmed-article:2526700 | pubmed:meshHeading | pubmed-meshheading:2526700-... | lld:pubmed |
| pubmed-article:2526700 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2526700 | pubmed:articleTitle | Allogenic induction of thromboplastin synthesis in monocytes and endothelial cells. Biphasic effect of cyclosporin A. | lld:pubmed |
| pubmed-article:2526700 | pubmed:affiliation | Surgical Department B, Rikshospitalet, Oslo, Norway. | lld:pubmed |
| pubmed-article:2526700 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2526700 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
