Linked Life Data

2526594

Source:http://linkedlifedata.com/resource/pubmed/id/2526594

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Pt 2
pubmed:dateCreated
1989-8-16
pubmed:abstractText
In freshwater-acclimated American eels (Anguilla rostrata LeSueur), ovine prolactin and grafts of the part of the pituitary gland containing the prolactin cells induced hypercalcemia. The hypercalcemia was associated with increased uptake of calcium from the water (resulting from increased influx and decreased efflux) and with enhanced high-affinity Ca2+-adenosinetriphosphatase (ATPase) activity in the gills, the putative biochemical correlate of the branchial Ca2+ pump. Kinetic analyses of ATPase-mediated Ca2+ transport in plasma membrane vesicles of branchial epithelium provided evidence that prolactin enhanced the maximum velocity of the Ca2+ pump. Prolactin treatments raised plasma cortisol levels slightly but significantly in eels. However, cortisol per se was not hypercalcemic in eels and did not stimulate the branchial Ca2+ pump. We conclude that the hypercalcemic potency of prolactin in fish relates to its stimulatory action on active Ca2+ transport in the gills.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
257
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R74-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Calcitropic actions of prolactin in freshwater North American eel (Anguilla rostrata LeSueur).
pubmed:affiliation
Department of Animal Physiology, Faculty of Science, University of Nijmegen, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't