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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-8-14
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pubmed:abstractText |
Levels of anticardiolipin antibodies (ACA) were measured in 55 patients with haemophilia A in serum samples obtained in 1983 and in 1987. Twenty-one patients were negative for anti HIV-1 antibodies in 1983 and remained negative in 1987; 34 patients had anti HIV-1 antibodies in 1983; 17 of these latter patients remained asymptomatic, whereas 17 patients developed ARC or AIDS during the 4 years follow-up. Thirteen anti HIV-1 negative patients had elevated ACA levels in 1983; subsequently, a significant decrease was observed in all these subjects (p less than 0.001). All anti HIV-1 positive patients had elevated ACA levels in 1983; normal values were found in 9 patients in 1987. Yet, these changes were not significant (p greater than 0.05). ACA levels were significantly higher in HIV-1 infected patients than in those without anti HIV-1 antibodies (p less than 0.05). There was no difference of ACA levels between the two anti HIV-1 positive patient groups, be it in 1983 or be it in 1987 (p greater than 0.05). There was no correlation of ACA levels with serum IgG concentrations, CD4+ lymphocytes, or the consumption of factor VIII concentrates.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0340-6245
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
81-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2526388-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:2526388-Adolescent,
pubmed-meshheading:2526388-Adult,
pubmed-meshheading:2526388-Autoantibodies,
pubmed-meshheading:2526388-Cardiolipins,
pubmed-meshheading:2526388-Child,
pubmed-meshheading:2526388-Cohort Studies,
pubmed-meshheading:2526388-Factor VIII,
pubmed-meshheading:2526388-HIV Seropositivity,
pubmed-meshheading:2526388-HIV-1,
pubmed-meshheading:2526388-Hemophilia A,
pubmed-meshheading:2526388-Humans,
pubmed-meshheading:2526388-Immunoglobulin G,
pubmed-meshheading:2526388-Leukocyte Count,
pubmed-meshheading:2526388-Middle Aged,
pubmed-meshheading:2526388-Prognosis,
pubmed-meshheading:2526388-Radioimmunoassay,
pubmed-meshheading:2526388-T-Lymphocytes, Helper-Inducer
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pubmed:year |
1989
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pubmed:articleTitle |
Anticardiolipin antibodies are elevated in HIV-1 infected haemophiliacs but do not predict for disease progression.
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pubmed:affiliation |
First Medical Clinic, University of Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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