pubmed-article:2524380 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2524380 | lifeskim:mentions | umls-concept:C0330390 | lld:lifeskim |
pubmed-article:2524380 | lifeskim:mentions | umls-concept:C0025936 | lld:lifeskim |
pubmed-article:2524380 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
pubmed-article:2524380 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
pubmed-article:2524380 | lifeskim:mentions | umls-concept:C0034790 | lld:lifeskim |
pubmed-article:2524380 | lifeskim:mentions | umls-concept:C1704410 | lld:lifeskim |
pubmed-article:2524380 | lifeskim:mentions | umls-concept:C1524075 | lld:lifeskim |
pubmed-article:2524380 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
pubmed-article:2524380 | lifeskim:mentions | umls-concept:C0337112 | lld:lifeskim |
pubmed-article:2524380 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:2524380 | pubmed:dateCreated | 1989-7-3 | lld:pubmed |
pubmed-article:2524380 | pubmed:abstractText | To study T cell tolerance, transgenic mice were generated that expressed the Mlsa-reactive T cell receptor (TCR) beta chain V beta 8.1 (cDNA) under the control of the H-2Kb promoter/immunoglobulin heavy chain enhancer on approximately 90% of peripheral T cells. In transgenic mice bearing Mlsa, thymocytes expressing the TCR at a high density were deleted and the percentage of Thy 1.2+ lymph node cells was reduced. The CD4/CD8 ratio of mature T cells was reversed in Mlsa and Mlsb transgenic mice independent of the H-2. RNA analysis and immunofluorescence with TCR V beta-specific antibodies revealed that expression of endogenous TCR beta genes was suppressed. Both Mlsa and Mlsb TCR beta chain transgenic mice mounted a T-cell-dependent IgG response against viral antigens, whereas the capacity to generate alloreactive and virus-specific cytotoxic T cells was impaired in TCR beta chain transgenic Mlsa, but not in transgenic Mlsb mice. | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:language | eng | lld:pubmed |
pubmed-article:2524380 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2524380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2524380 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2524380 | pubmed:month | Mar | lld:pubmed |
pubmed-article:2524380 | pubmed:issn | 0261-4189 | lld:pubmed |
pubmed-article:2524380 | pubmed:author | pubmed-author:LangRR | lld:pubmed |
pubmed-article:2524380 | pubmed:author | pubmed-author:ZinkernagelR... | lld:pubmed |
pubmed-article:2524380 | pubmed:author | pubmed-author:MaoT STS | lld:pubmed |
pubmed-article:2524380 | pubmed:author | pubmed-author:HengartnerHH | lld:pubmed |
pubmed-article:2524380 | pubmed:author | pubmed-author:BürkiKK | lld:pubmed |
pubmed-article:2524380 | pubmed:author | pubmed-author:PircherHH | lld:pubmed |
pubmed-article:2524380 | pubmed:author | pubmed-author:RüediEE | lld:pubmed |
pubmed-article:2524380 | pubmed:author | pubmed-author:BallhausenWW | lld:pubmed |
pubmed-article:2524380 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2524380 | pubmed:volume | 8 | lld:pubmed |
pubmed-article:2524380 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2524380 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2524380 | pubmed:pagination | 719-27 | lld:pubmed |
pubmed-article:2524380 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:meshHeading | pubmed-meshheading:2524380-... | lld:pubmed |
pubmed-article:2524380 | pubmed:year | 1989 | lld:pubmed |
pubmed-article:2524380 | pubmed:articleTitle | T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice. | lld:pubmed |
pubmed-article:2524380 | pubmed:affiliation | Department of Experimental Pathology, University Hospital, Zürich, Switzerland. | lld:pubmed |
pubmed-article:2524380 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2524380 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2524380 | lld:pubmed |