Linked Life Data

2521712

Source:http://linkedlifedata.com/resource/pubmed/id/2521712

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-3-23
pubmed:abstractText
Calcium phosphate ceramics might replace bone grafts in orthopaedic surgery. The chemical determination of these materials is now well known, and world-wide animal experiments as well as our own experience have proven that these products are both biocompatible and bioactive. The early chemical and physico-chemical mechanisms of interaction between calcium phosphate ceramics and bone tissue and biological fluids at the site of implantation are numerous (degradation, dissolution, crystal precipitation). These processes precede the cellular mechanisms of osteogenesis which take place during contact with the materials and define osteoconduction. When implanted in a bony environment, the ceramic ensures the formation of a genuine bone which within a few months will acquire all the characteristics of a normal lamellated bone with areas of apposition and resorption during remodeling. However, the mechanical characteristics of calcium phosphate ceramics do not permit an early loading, and they should only be used to fill bone cavities. In vertebral arthrodesis they must be implanted in stress-free areas and combined with strong and stable appliances. To benefit from the special bioactivity of calcium phosphate ceramics, research workers are now turning towards the treatment of metal alloys or composite fibres surfaces as well as of calcium phosphate complexes and extracellular matrix constituents (collagen, proteoglycans, etc.).
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0755-4982
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
28-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Calcium phosphate ceramics in orthopedic surgery].
pubmed:affiliation
Clinique orthopédique chirurgicale, CHR Saint-Jacques, Nantes.
pubmed:publicationType
Journal Article, English Abstract