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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1989-2-17
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pubmed:abstractText |
Qualitative and quantitative expression of m.RNA coding for Peptidyl-Glycine alpha-Amidating Monooxygenase (PAM) in the developing rat pancreas was investigated by Northern and dot blot hybridization, with a bovine PAM c.DNA probe (0.7 kb fragment). A specific hybridization signal was evidenced for a 3.7 kb m.RNA species. Measurement of PAM m. RNA rate during the rat pancreas ontogenesis revealed a biphasic profile which appeared corelated with that of gastrin and TRH m.RNA respectively. On the other hand, streptozotocin-treatment resulted in a 50% decrease of PAM m.RNA levels.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
16
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pubmed:volume |
158
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
244-50
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:2521448-Aging,
pubmed-meshheading:2521448-Animals,
pubmed-meshheading:2521448-Animals, Newborn,
pubmed-meshheading:2521448-Blotting, Northern,
pubmed-meshheading:2521448-DNA Probes,
pubmed-meshheading:2521448-Mixed Function Oxygenases,
pubmed-meshheading:2521448-Multienzyme Complexes,
pubmed-meshheading:2521448-Nucleic Acid Hybridization,
pubmed-meshheading:2521448-Oxidoreductases Acting on CH-NH Group Donors,
pubmed-meshheading:2521448-Pancreas,
pubmed-meshheading:2521448-RNA, Messenger,
pubmed-meshheading:2521448-Rats,
pubmed-meshheading:2521448-Rats, Inbred Strains,
pubmed-meshheading:2521448-Streptozocin
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pubmed:year |
1989
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pubmed:articleTitle |
Ontogenetic expression of peptidyl-glycine alpha-amidating monooxygenase mRNA in the rat pancreas.
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pubmed:affiliation |
Laboratoire de Neuroendocrinologie Expérimentale, INSERM U, 297, Faculté de Médecine Nord, Marseille, France.
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pubmed:publicationType |
Journal Article
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