Linked Life Data

2519370

Source:http://linkedlifedata.com/resource/pubmed/id/2519370

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1991-12-23
pubmed:abstractText
We studied genetic polymorphism of isoniazid acetylation in 47 tuberculous patients treated with 4 drugs between Aug 1987 and Dec 1988. Inactivation of isoniazid was estimated from urine samples after administration of the drug (10 mg/kg). There were 18 slow and 29 fast acetylators. The frequency of the slow mutant gene was estimated at 0.612, which is intermediate between values found in american natives (0.46) and western europeans (0.73). No associations of the presence of slow gene with sex, ABO group, ancestors, socioeconomic level, undernutrition, alcoholism or tobacco consumption were found.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0034-9887
pubmed:author
pubmed:issnType
Print
pubmed:volume
117
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1339-43
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Genetic polymorphism of isoniazid acetylation in Chilean patients with tuberculosis].
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't