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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1991-11-12
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pubmed:abstractText |
Human triple-lumen intestinal perfusion was used to compare water and solute absorption from the oral rehydration solution (ORS) most widely used in the United Kingdom and a new experimental hypotonic ORS (HYPO-ORS). HYPO-ORS (osmolality 210 mOsm/kg) promoted significantly greater water absorption than UK-ORS (7.03 +/- 1.1 vs 2.73 +/- 1.0 ml cm-1 h-1; P less than 0.01). HYPO-ORS produced net sodium and chloride absorption whereas the low sodium UK-ORS produced a net secretion of these ions. Bicarbonate absorption was also greater from HYPO-ORS although potassium and glucose absorption were similar from both solutions. This study suggests that UK-ORS may not promote optimal water and solute absorption and that clinical studies with HYPO-ORS are indicated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Electrolytes,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Hypotonic Solutions,
http://linkedlifedata.com/resource/pubmed/chemical/Rehydration Solutions,
http://linkedlifedata.com/resource/pubmed/chemical/Water
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0269-2813
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
565-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2518870-Adult,
pubmed-meshheading:2518870-Electrolytes,
pubmed-meshheading:2518870-Female,
pubmed-meshheading:2518870-Glucose,
pubmed-meshheading:2518870-Great Britain,
pubmed-meshheading:2518870-Humans,
pubmed-meshheading:2518870-Hypotonic Solutions,
pubmed-meshheading:2518870-Intestines,
pubmed-meshheading:2518870-Male,
pubmed-meshheading:2518870-Osmolar Concentration,
pubmed-meshheading:2518870-Perfusion,
pubmed-meshheading:2518870-Rehydration Solutions,
pubmed-meshheading:2518870-Water
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pubmed:year |
1989
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pubmed:articleTitle |
Efficacy of a standard United Kingdom oral rehydration solution (ORS) and a hypotonic ORS assessed by human intestinal perfusion.
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pubmed:affiliation |
Department of Gastroenterology, St Bartholomew's Hospital, West Smithfield, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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