Linked Life Data

2517711

Source:http://linkedlifedata.com/resource/pubmed/id/2517711

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-7-11
pubmed:abstractText
In 12 patients with moderate chagasic megaesophagus the lower esophageal sphincter pressure was studied under basal conditions and after i. v. infusion of pentagastrin by open tips infused rapid pull through manometry. Pentagastrin was infused in graded doses of 0.5, 1.0, 2.0 and 4.0 micrograms/kg/h. Results were compared with those of 12 healthy controls. Mean basal pressure in the megaesophagus group was significantly higher (p less than 0.05) than in the control group (36.2 +/- 2.5 and 27.4 +/- 1.8 cmH2O, respectively). Following pentagastrin infusion all the values of the lower esophageal sphincter pressure were significantly higher in the chagasic group (p less than 0.05). The plateau was achieved with 0.5 micrograms/kg/h in the control group and with 1.0 micrograms/kg/h in the chagasic group (p less than 0.05). Furthermore, the patients with megaesophagus needed a higher dose of pentagastrin to achieve the maximal contraction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0041-8781
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
178-80
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Response of the lower esophageal sphincter to pentagastrin on patients with megaesophagus secondary to Chagas' disease.
pubmed:publicationType
Journal Article