Linked Life Data

2517326

Source:http://linkedlifedata.com/resource/pubmed/id/2517326

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1990-5-17
pubmed:abstractText
This study evaluates the direct effect of acetate upon ventilation during acetate-haemodialysis. Eight patients with end-stage renal failure who were receiving chronic haemodialysis treatment underwent acetate infusion for 1 h on a day outside a haemodialysis session. Ventilation was continuously measured using respiratory inductance plethysmography, starting 20 min before the infusion. Arterial blood samples were drawn and expired gases were analysed at regular intervals. After 1 h of acetate infusion, arterial pH increased rapidly and significantly from 7.38 +/- 0.01 to 7.49 +/- 0.01, the VCO2 and VO2 slightly decreased and increased respectively, resulting in a reduced respiratory exchange ratio from 0.81 +/- 0.04 to 0.69 +/- 0.05. Ventilation slightly decreased only after 60 min, whereas the breathing pattern remained normal; neither apnoea periods nor periodic breathing were observed. We conclude that the hypoventilation and irregular breathing encountered in acetate-cuprophane haemodialysis is related to CO2/HCO3- unloading and the occurrence of complement-activation-induced hypoxaemia rather than to the small changes in VCO2, VO2 during metabolism of acetate.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0931-0509
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1060-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
The effect of acetate on ventilation in haemodialysis patients.
pubmed:affiliation
Department of Pulmonary Medicine, University Hospital Antwerp, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't