Linked Life Data

2515893

Source:http://linkedlifedata.com/resource/pubmed/id/2515893

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-3-21
pubmed:abstractText
When ovaries are removed prior to puberty, administration of exogenous 17 beta-estradiol (E2) decreases concentrations of luteinizing hormone (LH) below that of ovariectomized heifers receiving no E2. Subsequent to the time age-matched intact heifers reach puberty, exogenous E2 increases secretion of LH in ovariectomized heifers above that of ovariectomized heifers receiving no E2. The hypothesis that E2 would inhibit gonadotropin secretion in bovine males during the time E2 no longer inhibited gonadotropin secretion in age-matched bovine females was tested. Males (n = 12) and females (n = 12) were gonadectomized at 241 +/- 3 days of age, and half of each sex (6 males and 6 females) were administered a 27-cm E2 implant. An additional group of males (n = 6) and females (n = 6) remained intact and served as controls. Blood samples were collected (to quantify LH and follicle-stimulating hormone [FSH]) from all animals at 15-min intervals for 24 h at 1, 7, 13, 17, 21, 25, 29, 33, 37, and 43 wk after gonadectomy. Additional blood samples were collected twice weekly from control females to monitor progesterone and onset of corpus luteum function (451 days of age). E2 inhibited frequency of pulses of LH (p less than 0.01) and decreased mean concentration of LH and FSH (p less than 0.01) at Week 1 in gonadectomized males treated with E2 compared to gonadectomized males not administered E2.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-3363
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
626-34
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Estradiol influences on pattern of gonadotropin secretion in bovine males during the period of changed responses to estradiol feedback in age-matched females.
pubmed:affiliation
Animal Science Department, University of Nebraska, Lincoln 68583-0908.
pubmed:publicationType
Journal Article, Comparative Study