Linked Life Data

2514434

Source:http://linkedlifedata.com/resource/pubmed/id/2514434

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1990-2-21
pubmed:abstractText
N,N-Di(2-chlorethyl)hydrazides of the following alpha-amino-carboxylic acids were synthesized: glycine, valine, norvaline, lysine, phenylalanine, tyrosine, cystine, homocystine, aspartic and glutamic acid as well as the N,N-diethylhydrazides of glycine, phenylalanine and cystine. The N,N-di-(2-chlorethyl)hydrazides have a pronounced effect on solid tumours (tumour growth inhibition by 30-100%), whereas their inhibition activity with ascite tumours is negligible. N,N-diethylhydrazides show analogous but less expressed biological effect.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
608-11
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Synthesis and in vivo antitumor effect of N,N-di(2-chlorethyl) hydrazides of natural alpha-aminocarboxylic acids].
pubmed:affiliation
Institut für Molekularbiologie der Bulgarischen Akademie der Wissenschaften und Chemisch-technologische Hochschule, Sofia, VR Bulgarien.
pubmed:publicationType
Journal Article, English Abstract