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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1990-1-25
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pubmed:abstractText |
The present study was undertaken to determine the upper 95% confidence limits (CL) for titres of antibodies to streptolysin O (ASO) and streptococcal DNase B (ADNB) using 741 sera from a general population. The ASO titres in sera from children increased abruptly with increasing age, from a mean of 21 (CL 67) in infants of 3 years or less to 211 (CL 462) in children 7 to 8 years old. In children 9 to 12 years of age titres exhibited a plateau with mean values of 168-258 (CL 436-611). In individuals over 20 years the mean ASO titre diminished with increasing age, individuals of 70 years or more showing a mean titre of 83 (CL 169). A similar variation was seen for ADNB. Infants 3 years of age or younger exhibited no detectable ADNB whereas individuals 70 years or more had a mean titre of 11 (CL 91). A maximal mean ADNB titre of 184 (CL 706) was detected in 9-year-old-children. It was concluded that age-related reference values for anti-streptococcal antibodies increase the clinical relevance of the tests.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Deoxyribonucleases,
http://linkedlifedata.com/resource/pubmed/chemical/Streptolysins,
http://linkedlifedata.com/resource/pubmed/chemical/deoxyribonuclease B,
http://linkedlifedata.com/resource/pubmed/chemical/streptolysin O
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0934-9723
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
792-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2512149-Adolescent,
pubmed-meshheading:2512149-Adult,
pubmed-meshheading:2512149-Aged,
pubmed-meshheading:2512149-Aging,
pubmed-meshheading:2512149-Antibodies, Bacterial,
pubmed-meshheading:2512149-Bacterial Proteins,
pubmed-meshheading:2512149-Child,
pubmed-meshheading:2512149-Child, Preschool,
pubmed-meshheading:2512149-Deoxyribonucleases,
pubmed-meshheading:2512149-Female,
pubmed-meshheading:2512149-Humans,
pubmed-meshheading:2512149-Male,
pubmed-meshheading:2512149-Middle Aged,
pubmed-meshheading:2512149-Streptococcus,
pubmed-meshheading:2512149-Streptolysins
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pubmed:year |
1989
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pubmed:articleTitle |
Age-related variations in anti-streptococcal antibody levels.
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pubmed:affiliation |
Department of Medical Microbiology, University of Lund, Malmö General Hospital, Sweden.
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pubmed:publicationType |
Journal Article
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