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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions |
umls-concept:C0015780,
umls-concept:C0018061,
umls-concept:C0019932,
umls-concept:C0025344,
umls-concept:C0030685,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0205112,
umls-concept:C0205653,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C0733758,
umls-concept:C1283071,
umls-concept:C1521828,
umls-concept:C1561960,
umls-concept:C1948053,
umls-concept:C1963578,
umls-concept:C2347804
|
| pubmed:issue |
10
|
| pubmed:dateCreated |
1989-10-31
|
| pubmed:abstractText |
There are situations in which adult female rats release increased amounts of follicle-stimulating hormone (FSH) independent of increased luteinizing hormone (LH) release. This results from, at least in part, a selective increase in the basal FSH release rate. We investigated whether an increase in the basal FSH release rate is contributory to the rise in serum FSH levels which occurs independent of a rise in serum LH levels in the immature female rat. Rats had high serum FSH concentrations on days 7 and 15 after birth, low serum FSH levels on day 23, and low serum LH levels on all three days. In contrast, anterior pituitary gland (APG) FSH and LH concentrations and contents increased from day 7 to day 15 and the contents increased further from day 15 to day 23. Similarly, basal FSH and LH release rates per mg APG or per APG, as assessed by measurement of FSH and LH released into culture medium containing APG(s) from different aged rats, increased from day 7 to day 15 but did not increase further between days 15 and 23. The results indicate that unlike situations observed to date in adult female rats, a mechanism(s) other than an increase in the basal FSH release rate is involved in selective FSH release in the immature female rat.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0024-3205
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
45
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
863-8
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:2507844-Aging,
pubmed-meshheading:2507844-Animals,
pubmed-meshheading:2507844-Animals, Newborn,
pubmed-meshheading:2507844-Body Weight,
pubmed-meshheading:2507844-Female,
pubmed-meshheading:2507844-Follicle Stimulating Hormone,
pubmed-meshheading:2507844-Luteinizing Hormone,
pubmed-meshheading:2507844-Organ Size,
pubmed-meshheading:2507844-Pituitary Gland, Anterior,
pubmed-meshheading:2507844-Rats,
pubmed-meshheading:2507844-Rats, Inbred Strains
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
Basal gonadotropin hormone release rates during the period of selective follicle-stimulating hormone release in the juvenile female rat.
|
| pubmed:affiliation |
Department of Anatomy, University of South Carolina, School of Medicine, Columbia 29208.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|