Linked Life Data

2507096

Source:http://linkedlifedata.com/resource/pubmed/id/2507096

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1989-11-17
pubmed:abstractText
Recently Avissar et al. have established that Li+ can inhibit G proteins implicated in brain function. In order to investigate the effect of Li+ on transducin, the evolution of the electroretinogram (ERG) recorded on isolated rat retina has been studied in presence of lithium. Results indicate that 10(-5) M Li+ had no effect on ERG while 10(-3) M Li+, which corresponds to therapeutic blood levels, significantly decreases ERG amplitude. This effect being nearly totally inhibited by cholera toxin (75 micrograms/l), it is concluded that Li+ acts on transducin and so inhibits the visual transduction process.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0764-4469
pubmed:author
pubmed:issnType
Print
pubmed:volume
309
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
289-94
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Inhibition of transducin by lithium: electrophysiological demonstration using the isolated retina].
pubmed:affiliation
Laboratoire de Biophysique, I.N.S.E.R.M. U. n. 71, Facultés de Médecine et de Pharmacie, Clermont-Ferrand.
pubmed:publicationType
Journal Article, English Abstract