| pubmed-article:2506339 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2506339 | lifeskim:mentions | umls-concept:C0036945 | lld:lifeskim |
| pubmed-article:2506339 | lifeskim:mentions | umls-concept:C0008524 | lld:lifeskim |
| pubmed-article:2506339 | lifeskim:mentions | umls-concept:C0301715 | lld:lifeskim |
| pubmed-article:2506339 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:2506339 | lifeskim:mentions | umls-concept:C1326356 | lld:lifeskim |
| pubmed-article:2506339 | lifeskim:mentions | umls-concept:C1549542 | lld:lifeskim |
| pubmed-article:2506339 | pubmed:dateCreated | 1989-10-25 | lld:pubmed |
| pubmed-article:2506339 | pubmed:abstractText | 1. The uptake of neutral amino acids from the blood into the cells of the choroid plexus was studied by means of the rapid (less than 40 s) single-circulation paired-tracer dilution technique in the isolated perfused choroid plexus of the sheep. 2. The study provides the first direct evidence for the carrier-mediated entry of neutral amino acids from blood into the cells of the choroid plexus. 3. In the terms of Christensen's classification the presence of L-amino acid carrier systems for large neutral amino acids with bulky side chains has been demonstrated. 4. No measurable uptake of [14C]methyl amino isobutyric acid ([14C]MeAIB) during a single passage through the choroid plexus circulation was demonstrated which indicates the probable absence of a significant 'A' transport system. 5. The uptake of small neutral amino acids such as glycine and L-alanine was shown to be carrier-mediated. Results suggest that these amino acids are mainly transported by the glycine and ASC carrier systems, respectively. 6. The results suggest that there is a similarity between the transport systems for neutral amino acids on the blood side of both the blood-brain barrier and blood-cerebrospinal fluid barrier, the exception being for the presence of a glycine carrier on the blood side of the choroid plexus. | lld:pubmed |
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| pubmed-article:2506339 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2506339 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2506339 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2506339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:2506339 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2506339 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:2506339 | pubmed:issn | 0022-3751 | lld:pubmed |
| pubmed-article:2506339 | pubmed:author | pubmed-author:SegalM BMB | lld:pubmed |
| pubmed-article:2506339 | pubmed:author | pubmed-author:ZlokovicB VBV | lld:pubmed |
| pubmed-article:2506339 | pubmed:author | pubmed-author:PrestonJ EJE | lld:pubmed |
| pubmed-article:2506339 | pubmed:author | pubmed-author:WalleyG JGJ | lld:pubmed |
| pubmed-article:2506339 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2506339 | pubmed:volume | 408 | lld:pubmed |
| pubmed-article:2506339 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2506339 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2506339 | pubmed:pagination | 31-43 | lld:pubmed |
| pubmed-article:2506339 | pubmed:dateRevised | 2010-8-25 | lld:pubmed |
| pubmed-article:2506339 | pubmed:meshHeading | pubmed-meshheading:2506339-... | lld:pubmed |
| pubmed-article:2506339 | pubmed:meshHeading | pubmed-meshheading:2506339-... | lld:pubmed |
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| pubmed-article:2506339 | pubmed:meshHeading | pubmed-meshheading:2506339-... | lld:pubmed |
| pubmed-article:2506339 | pubmed:meshHeading | pubmed-meshheading:2506339-... | lld:pubmed |
| pubmed-article:2506339 | pubmed:meshHeading | pubmed-meshheading:2506339-... | lld:pubmed |
| pubmed-article:2506339 | pubmed:meshHeading | pubmed-meshheading:2506339-... | lld:pubmed |
| pubmed-article:2506339 | pubmed:meshHeading | pubmed-meshheading:2506339-... | lld:pubmed |
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| pubmed-article:2506339 | pubmed:meshHeading | pubmed-meshheading:2506339-... | lld:pubmed |
| pubmed-article:2506339 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2506339 | pubmed:articleTitle | Neutral amino acid uptake by the isolated perfused sheep choroid plexus. | lld:pubmed |
| pubmed-article:2506339 | pubmed:affiliation | Sherrington School of Physiology, United Medical School of Guy's Hospitals, London. | lld:pubmed |
| pubmed-article:2506339 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2506339 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:2506339 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
