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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1978-5-8
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pubmed:abstractText |
Samples from 260 non-jaundiced patients with elevated plasma alkaline phosphatase activities were analysed for gamma-glutamyltransferase and 5'-nucleotidase activity, and for alkaline phosphatase isoenzyme pattern. The plasma gamma-glutamyltransferase activity was found to be a more sensitive index than that of plasma 5'-nucleotidase in confirming the presence of a liver component of the elevated plasma alkaline phosphatase. If the gamma-glutamyltransferase level is normal it is probable that the increase in plasma alkaline phosphatase activity is of bone origin. However, and elevated gamma-glutamyltransferase result does not exclude a bone component; in this situation plasma alkaline phosphatase isoenzymes should be estimated. The causes of elevated activities of plasma alkaline phosphatase, 5'-nucleotidase and gamma-glutamyltransferase, found in this investigation were generally the same as those found by other worker. The effect of treatment by drugs on gamma-glutamyltransferase, an inducible enzyme, needs more investigation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0004-5632
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
86-90
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:25039-Adult,
pubmed-meshheading:25039-Alkaline Phosphatase,
pubmed-meshheading:25039-Bone Diseases,
pubmed-meshheading:25039-Bone and Bones,
pubmed-meshheading:25039-Clinical Enzyme Tests,
pubmed-meshheading:25039-Female,
pubmed-meshheading:25039-Humans,
pubmed-meshheading:25039-Isoenzymes,
pubmed-meshheading:25039-Liver,
pubmed-meshheading:25039-Liver Diseases,
pubmed-meshheading:25039-Male,
pubmed-meshheading:25039-Nucleotidases,
pubmed-meshheading:25039-gamma-Glutamyltransferase
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pubmed:year |
1978
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pubmed:articleTitle |
Origin of an elevated plasma alkaline phosphatase activity in non-jaundiced patients.
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pubmed:publicationType |
Journal Article
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