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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1989-7-5
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pubmed:abstractText |
Thirty-one patients affected by advanced ALL entered this study. Twenty (1 in I CR, 9 in II CR, 6 in III CR and 4 extramedullary relapses) were treated with the BMVC conditioning regimen. Eleven (9 in II CR, 2 in III CR) received the Busulfan plus Cytoxan conditioning regimen. Asta-Z 7654-purged marrow was reinfused at day 0. Both protocols were well tolerated. Two patients treated with the BMVC regimen died in aplasia from sepsis; 1 patient died in CR 5 months after transplantation, 13 relapsed after a median time of 4 months (range 1-31). Four patients are in CCR with a median follow-up of 16 months (range 11-24). In the BU + CY treated group no toxic deaths were observed. Four patients relapsed after a median of 3 months (range 2-7) and 7 are in CCR with a median follow-up of 5 months (range 2-28).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0390-6078
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
67-70
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2498186-Adolescent,
pubmed-meshheading:2498186-Adult,
pubmed-meshheading:2498186-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:2498186-Bone Marrow Transplantation,
pubmed-meshheading:2498186-Busulfan,
pubmed-meshheading:2498186-Carmustine,
pubmed-meshheading:2498186-Child,
pubmed-meshheading:2498186-Combined Modality Therapy,
pubmed-meshheading:2498186-Cyclophosphamide,
pubmed-meshheading:2498186-Cytarabine,
pubmed-meshheading:2498186-Drug Resistance,
pubmed-meshheading:2498186-Etoposide,
pubmed-meshheading:2498186-Female,
pubmed-meshheading:2498186-Humans,
pubmed-meshheading:2498186-Male,
pubmed-meshheading:2498186-Mitoxantrone,
pubmed-meshheading:2498186-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:2498186-Preoperative Care,
pubmed-meshheading:2498186-Transplantation, Autologous
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pubmed:articleTitle |
Results of two different conditioning regimens followed by ABMT in refractory acute lymphoblastic leukemia.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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