Linked Life Data

2497798

Source:http://linkedlifedata.com/resource/pubmed/id/2497798

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-6-29
pubmed:abstractText
The permeability of artificial unilamellar vesicles and of plasma membrane vesicles from homogenized yeast in aqueous solutions of polyene antibiotics (amphotericin B and lucensomycin) was studied by measuring proton leakage by a pH-stat method. Micromolar concentrations of amphotericin B induced a remarkable proton efflux from the vesicles. Lucensomycin exerted similar effects only at 100 times higher concentrations. The latter antibiotic, at concentrations one order of magnitude lower than those necessary to induce a detectable proton efflux, seemed to protect the vesicles from the subsequent permeabilizing action of amphotericin B.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0300-9084
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-61
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Combined effects exerted by amphotericin B and lucensomycin on cation permeability in a unilamellar vesicle system.
pubmed:affiliation
Dipartimento di Scienze Biochimiche, Città Universitaria, Rome, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't