rdf:type |
|
lifeskim:mentions |
umls-concept:C0019693,
umls-concept:C0020852,
umls-concept:C0021699,
umls-concept:C0030956,
umls-concept:C0445604,
umls-concept:C0871261,
umls-concept:C0913822,
umls-concept:C0913823,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
11
|
pubmed:dateCreated |
1989-6-22
|
pubmed:abstractText |
The IgG subclass distribution to the E34/E32 peptides, derived from the HIV-1 glycoprotein 41 transmembrane protein, was analyzed in ELISA. Sera from individuals at different stages of the disease were assayed. A restricted subclass response of mainly IgG1 and IgG2 was found. The subclass response was of a different type than the one observed to HIV whole Ag and to a synthetic peptide from the C'-terminal part of the HIV-1 p24 core protein. An increased subclass restriction was observed in progressed stages of the disease.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0022-1767
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
142
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3809-14
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2497181-Amino Acid Sequence,
pubmed-meshheading:2497181-Amino Acids,
pubmed-meshheading:2497181-Antibody Specificity,
pubmed-meshheading:2497181-Binding Sites, Antibody,
pubmed-meshheading:2497181-HIV Antibodies,
pubmed-meshheading:2497181-HIV Antigens,
pubmed-meshheading:2497181-HIV Core Protein p24,
pubmed-meshheading:2497181-HIV Envelope Protein gp41,
pubmed-meshheading:2497181-HIV-1,
pubmed-meshheading:2497181-Humans,
pubmed-meshheading:2497181-Immunoglobulin G,
pubmed-meshheading:2497181-Membrane Proteins,
pubmed-meshheading:2497181-Molecular Sequence Data,
pubmed-meshheading:2497181-Peptides,
pubmed-meshheading:2497181-Retroviridae Proteins,
pubmed-meshheading:2497181-Viral Envelope Proteins
|
pubmed:year |
1989
|
pubmed:articleTitle |
IgG subclass responses to a transmembrane protein (gp41) peptide in HIV infection.
|
pubmed:affiliation |
Department of Virology, Karolinska Institute, Stockholm, Sweden.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|