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pubmed:abstractText |
Low-dose pretreatments with maleic hydrazide, mitomycin C, and N-methyl-N-nitrosourea or sublethal heat shock were tested with regard to their effect on sister-chromatid exchange (SCE) induction by high doses of the same mutagens administered 2 h later to root-tip meristems of Vicia faba. Consecutive treatments resulted in either additive or, in a minority of experiments, in below-additive SCE frequencies. A model is proposed to explain the conflicting data reported on adaptation to SCE and aberration induction.
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