Linked Life Data

2494160

Source:http://linkedlifedata.com/resource/pubmed/id/2494160

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-4-24
pubmed:abstractText
Various anticonvulsant medications may have efficacy in the treatment of certain anxiety states as well as withdrawal syndromes occurring after the discontinuation of sedative-hypnotic drugs and alcohol. Preclinical studies and limited anecdotal evidence suggest that valproate may be more effective in controlling panic than carbamazepine. In small studies valproate and carbamazepine have been shown as possible effective agents in the treatment of alcohol withdrawal. Some treatment-resistant patients with panic disorder may respond well to trials of certain anticonvulsants. It is also possible that some patients in the heterogeneous generalized anxiety disorder category may respond to valproate and carbamazepine, particularly in light of the similarity between this type of anxiety and the symptoms of alcohol and sedative-hypnotic drug withdrawal. While benzodiazepines clearly have an important role in the treatment of anxiety and withdrawal states, the role of nonbenzodiazepine anticonvulsants is a promising one which needs to be further delineated with careful, controlled studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0160-6689
pubmed:author
pubmed:issnType
Print
pubmed:volume
50 Suppl
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
44-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Valproate in anxiety and withdrawal syndromes.
pubmed:affiliation
Department of Psychiatry and Behavioral Sciences, University Hospital, University of Washington, Seattle.
pubmed:publicationType
Journal Article, Clinical Trial, Review, Case Reports