Linked Life Data

2494159

Source:http://linkedlifedata.com/resource/pubmed/id/2494159

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-4-24
pubmed:abstractText
The author reports five cases of bipolar disorder in mentally retarded adults that were managed by treating the patients with divalproex sodium, a valproate derivative. Two patients had chronic mania (one of whom had Fragile X syndrome), two patients had rapid cycling illness (one of whom had an autistic disorder), and one patient had a classic bipolar disorder superimposed on an autistic disorder. Four of the patients had marked responses to valproate and the fifth patient had a moderate response. Valproate blood levels were within the usual therapeutic range of 50 micrograms/mL to 100 micrograms/mL. These results demonstrate the effectiveness of valproate in the treatment of mentally retarded patients with typical and atypical bipolar disorders.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0160-6689
pubmed:author
pubmed:issnType
Print
pubmed:volume
50 Suppl
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
40-3
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
The use of valproate in the treatment of mentally retarded persons with typical and atypical bipolar disorders.
pubmed:affiliation
Lutheran Center for Mental Health and Mental Retardation, Watertown, Mass.
pubmed:publicationType
Journal Article, Case Reports