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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1989-3-23
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pubmed:abstractText |
One hundred ninety-five consecutive children with Haemophilus influenzae meningitis were retrospectively reviewed to identify those patients at high risk of death or severe sequelae using a previously described clinical scoring system. One hundred sixty-nine children (86.7%) had prognostic scores less than or equal to 4.0 and all survived. Twenty-six patients (13.3%) had prognostic scores greater than or equal to 4.5 points. Five of these high-risk patients (2.6% overall) died as a direct result of their acute meningitis. Of the remaining 21 survivors, 15 were available for prospective, observer-blinded, follow-up evaluation, as compared with 15 low-risk control patients matched for age, sex, and year of admission. High-risk patients were significantly more likely to have more serious sequelae (2.0 +/- 2.1) as compared with low-risk controls (0.5 +/- 0.7). Those high-risk patients who by the choice of their treating physicians had received corticosteroids (and usually osmotic therapy as well) appeared to have outcomes similar to their matched low-risk controls and significantly better than those high-risk patients who did not receive such additional therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0002-922X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
143
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
307-11
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2492753-Adrenal Cortex Hormones,
pubmed-meshheading:2492753-Child,
pubmed-meshheading:2492753-Child, Preschool,
pubmed-meshheading:2492753-Drug Therapy, Combination,
pubmed-meshheading:2492753-Female,
pubmed-meshheading:2492753-Humans,
pubmed-meshheading:2492753-Infant,
pubmed-meshheading:2492753-Male,
pubmed-meshheading:2492753-Mannitol,
pubmed-meshheading:2492753-Meningitis, Haemophilus,
pubmed-meshheading:2492753-Prognosis,
pubmed-meshheading:2492753-Prospective Studies,
pubmed-meshheading:2492753-Retrospective Studies,
pubmed-meshheading:2492753-Risk Factors
|
pubmed:year |
1989
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pubmed:articleTitle |
Clinical identification and comparative prognosis of high-risk patients with Haemophilus influenzae meningitis.
|
pubmed:affiliation |
Children's Hospital Kempe Research Center, Children's Hospital of Denver, CO 80218.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|