rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1989-3-16
|
pubmed:abstractText |
In a crossover study 20 subjects (12 with non-toxic goiter) were given 150 micrograms levo-thyroxine (LT4) or a combination of 100 micrograms LT4 and 100 micrograms iodide daily for 8 weeks. Group I took 150 micrograms LT4 and group II the combination. After 4 weeks the two groups switched medications. A clinical examination, an intravenous TRH test and thyroid sonography were performed before the start of the study and 4 and 8 weeks thereafter. 150 micrograms LT4 daily resulted in significantly higher TSH suppression than the combination. A decrease in thyroid volume from 45 ml (mean range 24-85) to 26 ml (17-70 ml) was registered after as little as 4 weeks' therapy in 12 of 20 subjects with goiter.
|
pubmed:language |
ger
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0036-7672
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
14
|
pubmed:volume |
119
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
59-64
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2492674-Adult,
pubmed-meshheading:2492674-Drug Therapy, Combination,
pubmed-meshheading:2492674-Female,
pubmed-meshheading:2492674-Goiter,
pubmed-meshheading:2492674-Humans,
pubmed-meshheading:2492674-Iodine,
pubmed-meshheading:2492674-Male,
pubmed-meshheading:2492674-Thyroid Gland,
pubmed-meshheading:2492674-Thyroid Hormones,
pubmed-meshheading:2492674-Thyrotropin,
pubmed-meshheading:2492674-Thyrotropin-Releasing Hormone,
pubmed-meshheading:2492674-Thyroxine,
pubmed-meshheading:2492674-Ultrasonography
|
pubmed:year |
1989
|
pubmed:articleTitle |
[Thyroxine vs iodine and thyroxine. Comparison of the TSH suppression test].
|
pubmed:affiliation |
Abteilung Innere Medi?in, Endokrinologie und Stoffwechsel, Klinikum der Johannes-Gutenberg-Universität, Mainz.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract,
Controlled Clinical Trial
|