Linked Life Data

2490824

Source:http://linkedlifedata.com/resource/pubmed/id/2490824

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Suppl
pubmed:dateCreated
1991-8-26
pubmed:abstractText
Renal failure is a well-recognized complication of accelerated and malignant hypertension that can be prevented by appropriate antihypertensive therapy. The risk of renal disease in patients with milder forms of hypertension is less certain. Death certificate, insurance industry, and community-based observational studies provide little information with respect to the risk of kidney damage in the hypertensive patient. Randomized controlled trials of antihypertensive drug therapy provide equivocal results. The strongest evidence in support of the hypothesis that mild hypertension increases the risk of subsequent renal disease comes from analyses of the Hypertension Detection and Follow-up Program and the Medicare End-Stage Renal Disease (ESRD) Program. The risk of blood pressure-related ESRD appears to be especially high in blacks, independent of age, sex, and prevalence of hypertension. Although these results need to be confirmed, the data raise the possibility that the effects of high blood pressure on the kidney are different in blacks than in whites. Based on current trends, it is projected that the number of beneficiaries in the Medicare ESRD Program will continue to increase during the next 30-40 years and that the diagnosis of hypertensive ESRD will become increasingly common. Additional studies to characterize the relation between mild hypertension and subsequent risk of renal disease and to confirm the corresponding benefits of antihypertensive therapy are urgently needed.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0194-911X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
I19-27
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Hypertension as a risk factor for renal disease. Review of clinical and epidemiological evidence.
pubmed:affiliation
Department of Epidemiology, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Review