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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1991-1-8
|
| pubmed:abstractText |
Multivariate saccharide quantitative structure-activity relationships (QSARs) have been developed for two series of 9-hydroxyellipticine glycosides. In order to describe the structural variation of the glycoside moieties, thirteen chromatographic variables were used. Eleven D-glycosides and seven L-glycosides were used in separate QSARs to model 9-hydroxyellipticine glycoside antitumour activity against L 1210 leukemia. The multivariate partial least squares (PLS) method was used to establish the QSARs.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0904-213X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
43
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
286-9
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2486132-Animals,
pubmed-meshheading:2486132-Antineoplastic Agents,
pubmed-meshheading:2486132-Ellipticines,
pubmed-meshheading:2486132-Leukemia L1210,
pubmed-meshheading:2486132-Mice,
pubmed-meshheading:2486132-Multivariate Analysis,
pubmed-meshheading:2486132-Stereoisomerism,
pubmed-meshheading:2486132-Structure-Activity Relationship
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
A multivariate approach to saccharide quantitative structure-activity relationships exemplified by two series of 9-hydroxyellipticine glycosides.
|
| pubmed:affiliation |
Department of Organic Chemistry, Umeå University, Sweden.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|