Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1991-8-23
pubmed:abstractText
A spectrophotometric method is proposed for the determination of paracetamol in pure form and in tablets. The method depends on reaction of the drug with ammonium molybdate in strongly acidic medium to produce molybdenum blue. Effects of variables such as temperature, heating time, acidity and reagent concentration have been evaluated to permit selection of the most advantageous technique. Beer's law was followed for concentrations of up to 6 micrograms ml-1 of paracetamol and the detection limit (p = 0.05) was 0.10 microgram ml-1. The molar absorptivity at 670 nm was 2.6 x 10(4) l mol-1 cm-1 and the relevant Sandell's sensitivity of the reaction was 0.0059 microgram cm-2 per 0.001 absorbance unit. Statistical analysis of the results and comparison with results by the BP method of analysis are also reported.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0731-7085
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
577-84
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Spectrophotometric determination of paracetamol in pure form and in tablets.
pubmed:affiliation
Dipartimento di Chimica, Universita degli Studi Bari, Italy.
pubmed:publicationType
Journal Article