Linked Life Data

2484949

Source:http://linkedlifedata.com/resource/pubmed/id/2484949

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-5-23
pubmed:abstractText
Human cadaver eyes can be dehydrated by prolonged elevation of intraocular pressure (three to five hours) or by hyperosmotic Dextran over a 20- to 30-minute period. We divided four pairs of donor eyes into two groups (A and B) and dehydrated four corneas by each method. After corneal thinning to 500 to 600 microns, central corneal pachymetry was measured every ten minutes during the rehydration period for one hour, with each cornea pair being moistened at a different rate (every 30 seconds, 1 minute, 2.5 minutes or 5 minutes). The resultant increase in central corneal thickness noted by change in pachymetry (delta P) ranged from 12.4% to 14.7% over one hour between the two groups. delta P did not differ significantly between groups A and B, regardless of the varying rate of balanced salt solution irrigation of the corneas. Thus, it appears that either method of corneal dehydration provides comparable stability of corneal thinning for at least one hour to allow consistent corneal dynamics for experimental refractive surgery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1042-962X
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
41-2
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
Human cadaver corneal thinning for experimental refractive surgery.
pubmed:affiliation
Department of Ophthalmology, University of Minnesota, Minneapolis 55455.
pubmed:publicationType
Journal Article, Comparative Study