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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1990-5-18
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pubmed:abstractText |
Cholesterol-lowering activity of enzymatic hydrolysate of bagasse alkaline extract was studied in rats fed a cholesterol-enriched diet. The bagasse alkaline extract was found to be vulnerable to the enzymic attack of alpha-amylase. Thus the alkaline extract was degraded into two fractions: long-chain fraction (polysaccharides) and short-chain fraction (oligosaccharides). The long-chain fraction was active in lowering the serum cholesterol level while feeding the short-chain fraction resulted in a slightly elevated serum cholesterol level. The feeding by gavege of the long-chain fraction 12 h after the meal also was effective in lowering serum cholesterol concentration. These findings were compatible with the concept that the bagasse alkaline extract affect the cholesterol dynamics apart from input-output balance of cholesterol. Possible mechanisms responsible for the cholesterol-lowering activity of the extract were discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amylases,
http://linkedlifedata.com/resource/pubmed/chemical/Anticholesteremic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cellulose,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Extracts,
http://linkedlifedata.com/resource/pubmed/chemical/bagasse
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0301-4800
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
481-94
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2483730-Amylases,
pubmed-meshheading:2483730-Animals,
pubmed-meshheading:2483730-Anticholesteremic Agents,
pubmed-meshheading:2483730-Bacillus subtilis,
pubmed-meshheading:2483730-Body Weight,
pubmed-meshheading:2483730-Cellulose,
pubmed-meshheading:2483730-Cholesterol,
pubmed-meshheading:2483730-Diet, Atherogenic,
pubmed-meshheading:2483730-Feces,
pubmed-meshheading:2483730-Hydrolysis,
pubmed-meshheading:2483730-Liver,
pubmed-meshheading:2483730-Plant Extracts,
pubmed-meshheading:2483730-Rats
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pubmed:year |
1989
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pubmed:articleTitle |
Hypocholesterolemic activity of alpha-amylase hydrolysate of bagasse alkaline extract in rats fed atherogenic diet.
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pubmed:affiliation |
Department of Agricultural Chemistry, University of the Ryukyus, Okinawa, Japan.
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pubmed:publicationType |
Journal Article
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