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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1990-4-6
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pubmed:abstractText |
In 149 eyes with central retinal vein occlusion (CRVO), we prospectively investigated the role of routine, clinical electroretinography (ERG) in differentiating ischemic (60 eyes) from nonischemic CRVO (89 eyes). Single-flash photopic and scotopic ERGs were recorded. Data for the amplitudes and implicit times of a- and b-waves and for the b-/a-wave amplitude ratio were analyzed in detail. The study revealed that the best ERG parameter (for both photopic and scotopic ERG) for differentiating ischemic from nonischemic CRVO was a subnormal b-wave amplitude (reduced to less than or equal to 60% or by greater than or equal to 1 SD from the normal mean value, or less than or equal to 64%-69% of that in the fellow normal eye), with a sensitivity of 80%-90% and a specificity of 70%-80%. ERG findings were correlated with the relative afferent pupillary defect (RAPD). An RAPD of greater than or equal to 0.7 log units showed a sensitivity of 88% and a specificity of 90% in differentiating ischemic from nonischemic CRVO. ERG and RAPD findings showed a good correlation. The combined ERG and RAPD tests could differentiate 97%-100% of ischemic from nonischemic CRVO cases, with a specificity of about 70%.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0721-832X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
227
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
549-61
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2483144-Aged,
pubmed-meshheading:2483144-Aged, 80 and over,
pubmed-meshheading:2483144-Analysis of Variance,
pubmed-meshheading:2483144-Electroretinography,
pubmed-meshheading:2483144-Eye,
pubmed-meshheading:2483144-Follow-Up Studies,
pubmed-meshheading:2483144-Glaucoma,
pubmed-meshheading:2483144-Humans,
pubmed-meshheading:2483144-Ischemia,
pubmed-meshheading:2483144-Middle Aged,
pubmed-meshheading:2483144-Neovascularization, Pathologic,
pubmed-meshheading:2483144-Predictive Value of Tests,
pubmed-meshheading:2483144-Prospective Studies,
pubmed-meshheading:2483144-Pupil Disorders,
pubmed-meshheading:2483144-Regression Analysis,
pubmed-meshheading:2483144-Retinal Vein Occlusion
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pubmed:year |
1989
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pubmed:articleTitle |
Electroretinography in central retinal vein occlusion. Correlation of electroretinographic changes with pupillary abnormalities.
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pubmed:affiliation |
Department of Ophthalmology, University of Iowa, Iowa City 52242.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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