Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1990-3-26
pubmed:abstractText
T lymphocytes from rats with malignant fibrous histiocytoma at different stages of tumor growth were investigated for sensitization to bovine myelin basic protein (MBP). The immunological reactivity was assessed by a leukocyte adherence inhibition assay as an in vitro correlate of cellular immunity. We found that only T lymphocytes obtained 4 and 6 days after tumor transplantation are reactive to MBP (1-2 micrograms/ml). Since the sequence of the antigenic determinants from MBP is known, our findings may make it possible to select synthetic epitopes for generating cytotoxic T lymphocytes to these tumor cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0100-879X
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
721-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Cellular immunity to bovine myelin basic protein in rats bearing malignant fibrous histiocytoma.
pubmed:affiliation
Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceara, Fortaleza, CE, Brasil.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't