Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3 Suppl
pubmed:dateCreated
1990-1-23
pubmed:abstractText
We have examined serum alpha-fetoprotein (AFP) concentrations in the pre- and post-orthotopic liver transplantation (OLT) period of a population of 19 adult patients. (Five with secondary hepatic malignancy and fourteen with primary hepatic cancer). In pre-OLT, rises in serum AFP levels are indicatives for hepatocellular carcinoma (HCC): six of our nine cases of HCC were associated with the increase in serum AFP concentration, but none of the non-hepatocellular primary cancers and only one of the five secondary malignancy (hepatic metastasis of breast carcinoma with serum AFP values around 20 ng/ml). In pre-OLT, AFP values correlated with viable tumor mass rather than tumor:volume. In post-OLT, rises in AFP concentrations may be explained either by recurrent hepatic cancer or by hepatic post-necrotic regeneration. In this case, the increase in serum transaminasis is an important help for differential diagnosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0392-0208
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
132-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Role of serum alpha-fetoprotein in pre- and post-orthotopic liver transplantation (OLT) for malignant disease.
pubmed:publicationType
Journal Article, Comparative Study