Linked Life Data

248019

Source:http://linkedlifedata.com/resource/pubmed/id/248019

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
54
pubmed:dateCreated
1978-8-14
pubmed:abstractText
In the cat and goose, studies have been undertaken to determine the ultrastructure of airway epithelia, the concentration and distribution of the secretory cells which produce respiratory tract mucus, and the histochemistry of mucins located within cells and on their luminal surfaces. By electron microscopy all the 11 cell types so far described can be found in the airways of the cat but not the goose. Both goblet cells and submucosal glands are abundant in the cat whereas the trachea of goose lacks the latter, having instead abundant goblet cells many of which form 'intraepithelial glands'. Histochemically, the goblet cells of the cat and goose are similar in that they contain mucins with a predominance of sulphate esters. A surface mucosubstance can be demonstrated which, histochemically, is similar to that described in dog and man. Interestingly, this surface layer may be sloughed in response to an inhaled irritant such as ammonia and thereby contribute to the respiratory tract mucus recovered experimentally. Incorporation into macromolecules of radioactively labelled mucin precursors is assessed by autoradiography of tissue sections, and preliminary results of experiments designed to test the response of mucus-secreting cells to airway irritation and the parasympathomimetic drug, pilocarpine, are also presented.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-5208
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5-23
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Structure and function of mucus-secreting cells of cat and goose airway epithelium.
pubmed:publicationType
Journal Article, Comparative Study