Linked Life Data

2476256

Source:http://linkedlifedata.com/resource/pubmed/id/2476256

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-10-23
pubmed:abstractText
The expression of phenotypes of cultured cancer cells might be associated with cancer cell differentiation. By using the electron microscope and monoclonal antibodies against cytokeratins, PKK1, PKK2 and PKK3, the expression of cytokeratins and tonofilaments of normal embryonic esophageal epithelial cells and esophageal cancer cells were studied. Both PKK1 and PKK2 cytokeratins were detected in embryonic esophageal and esophageal cancer cells, but PKK3 was not present. This indicated that these were squamous but not glandular epithelial cells. Also, a much greater degree of expression of PKK1 and PKK2, tonofilaments and desmosomes was observed in differentiated embryonic squamous esophageal epithelial cells and in DMSO or retinamide induced differentiated esophageal cancer cells than in undifferentiated esophageal cancer cells.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1000-503X
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
129-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Correlation between esophageal cancer cell differentiation and expression of cytokeratin and tonofilament].
pubmed:publicationType
Journal Article, English Abstract