Linked Life Data

2475444

Source:http://linkedlifedata.com/resource/pubmed/id/2475444

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-10-3
pubmed:abstractText
By selective cloning of gene products newly expressed in the developing chick optic tectum, we have isolated cDNA clones encoding myelin basic protein (MBP). Three different transcripts of the corresponding single copy gene of 2.7 kb, 2.0 kb, and 1.1 kb were observed on Northern blots. In the developing optic lobe, the most abundant RNA (2.7 kb) was detected first at the 14th day in ovo. Nuclease S1 protection experiments revealed further heterogeneity of MBP transcripts, which result from alternative splicing of segments corresponding to the fifth and sixth exon of the homologous murine MBP gene. From these data, at least three different forms of MBP are predicted to exist in the chicken central nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0894-1491
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
241-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Developmental accumulation and heterogeneity of myelin basic protein transcripts in the chick visual system.
pubmed:affiliation
ZMBH, Universität Heidelberg, Federal Republic of Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't