Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
1989-8-11
pubmed:abstractText
The blood levels of tumour markers (alpha-foetoprotein and human chorionic gonadotropin) were determined and serial chest X-rays were obtained from 11 patients with germ cell tumours to study the growth of the tumours. Assuming an exponential growth pattern, the tumour marker levels and diameters of lung metastases were analysed. The use of a simple model made it possible to describe the time course of the change of tumour marker levels in blood before and during treatment. The analysis provided estimates of doubling times for marker-positive subpopulations, which were generally in accordance with the doubling times for lung metastases. The estimated doubling times had a log-normal mean value of 21.3 days, in agreement with the 19.5 days for embryonic tumours obtained in other studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0361-090X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
293-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
A simple mathematical model applied to describing tumour marker data.
pubmed:affiliation
Department of Oncology and Radiotherapy, Aalborg Regional Hospital, Denmark.
pubmed:publicationType
Journal Article