Linked Life Data

2472157

Source:http://linkedlifedata.com/resource/pubmed/id/2472157

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1989-8-3
pubmed:abstractText
If chemotherapy is effectively controlling microscopic distant metastases, then a reduced number of patients would experience treatment failure at distant sites. This study has used a group of 175 patients on a phase 3 Southwest Oncology Group trial for resectable advanced stage disease to test this hypothesis. In the group that failed, 52% of the standard group failed at distant sites as opposed to only 30% of the experimental group. This difference approaches statistical significance. These findings suggest that chemotherapy, although demonstrating some activity against microscopic distant disease, has not substantially altered the usual patterns of treatment failure for head and neck cancer. However, the assumption that the clinical responses noted with chemotherapy are having a positive influence on the frequency of occult distant disease was supported by our results.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0886-4470
pubmed:author
pubmed:issnType
Print
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
834-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Analysis of treatment failure patterns. A Southwest Oncology Group Study.
pubmed:affiliation
Department of Otolaryngology, Ohio State University, Columbus.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S.