Linked Life Data

2469594

Source:http://linkedlifedata.com/resource/pubmed/id/2469594

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-6-20
pubmed:abstractText
We have synthesized a dimeric analogue of substance P (SP) COOH-terminal nonapeptide fragment (D-SP-(3-11] and examined the in vivo and in vitro biological activities in the submaxillary gland of the rat. The dimer elicited an enhanced biological response as compared with receptor binding, showing 2.4-fold more potent receptor affinity than its monomer and 75-fold more potent in vivo salivary secretion activity.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
160
pubmed:owner
NLM
pubmed:authorsComplete
N
pubmed:pagination
413-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Dimeric substance P analogue shows a highly potent activity of the in vivo salivary secretion in the rat.
pubmed:affiliation
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't