|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1989-6-5
|
|
pubmed:abstractText |
Lomefloxacin (NY-198) [(+/-)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo -3- quinolinecarboxylic acid hydrochloride] strongly inhibited the growths of not only Gram-negative Escherichia coli but Gram-positive Staphylococcus aureus. In vivo and in vitro experiments showed deoxyribonucleic acid (DNA) synthesis was specifically inhibited by this drug in E. coli.
|
|
pubmed:language |
jpn
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0368-2781
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
42
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
193-9
|
|
pubmed:dateRevised |
2009-11-11
|
|
pubmed:meshHeading |
pubmed-meshheading:2468799-4-Quinolones,
pubmed-meshheading:2468799-Anti-Infective Agents,
pubmed-meshheading:2468799-Bacteria,
pubmed-meshheading:2468799-Bacterial Proteins,
pubmed-meshheading:2468799-DNA, Bacterial,
pubmed-meshheading:2468799-Escherichia coli,
pubmed-meshheading:2468799-Fluoroquinolones,
pubmed-meshheading:2468799-Microbial Sensitivity Tests,
pubmed-meshheading:2468799-Pseudomonas aeruginosa,
pubmed-meshheading:2468799-Quinolones,
pubmed-meshheading:2468799-RNA, Bacterial,
pubmed-meshheading:2468799-Staphylococcus aureus
|
|
pubmed:year |
1989
|
|
pubmed:articleTitle |
[Bactericidal action of lomefloxacin a new pyridonecarboxylic acid derivative].
|
|
pubmed:affiliation |
Department of Microbiology, Faculty of Pharmaceutical Sciences, Kanazawa University.
|
|
pubmed:publicationType |
Journal Article,
English Abstract
|
