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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1989-5-18
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pubmed:abstractText |
Production of human chorionic gonadotropin by sarcomas is an uncommon phenomenon that has rarely been documented. A case of a 26-year-old woman with osteosarcoma of the left fibula and high levels of serum beta-human chorionic gonadotropin (beta-HCG) is described. Immunoperoxidase staining showed numerous tumor cells reacting with the beta-HCG antibody. Immunohistochemical studies performed on ten additional osteosarcomas demonstrated another case in which some tumor cells presented immunoreactivity for beta-HCG. These results indicate that beta-HCG may be used as a marker of persistent or recurrent disease in those uncommon cases of osteosarcoma in which serum levels of beta-HCG are elevated at the onset of treatment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Chorionic Gonadotropin,
http://linkedlifedata.com/resource/pubmed/chemical/Chorionic Gonadotropin, beta...,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-9985
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
113
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
416-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2468324-Adult,
pubmed-meshheading:2468324-Bone Neoplasms,
pubmed-meshheading:2468324-Chorionic Gonadotropin,
pubmed-meshheading:2468324-Chorionic Gonadotropin, beta Subunit, Human,
pubmed-meshheading:2468324-Female,
pubmed-meshheading:2468324-Humans,
pubmed-meshheading:2468324-Immunohistochemistry,
pubmed-meshheading:2468324-Osteosarcoma,
pubmed-meshheading:2468324-Peptide Fragments,
pubmed-meshheading:2468324-Tumor Markers, Biological
|
pubmed:year |
1989
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pubmed:articleTitle |
Ectopic production of the beta-subunit of human chorionic gonadotropin in osteosarcoma.
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pubmed:affiliation |
Department of Pathology, University of Texas M. D. Anderson Hospital, Houston 77030.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|