| pubmed-article:2467888 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2467888 | lifeskim:mentions | umls-concept:C0036025 | lld:lifeskim |
| pubmed-article:2467888 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:2467888 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:2467888 | lifeskim:mentions | umls-concept:C2239176 | lld:lifeskim |
| pubmed-article:2467888 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:2467888 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:2467888 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:2467888 | lifeskim:mentions | umls-concept:C0301869 | lld:lifeskim |
| pubmed-article:2467888 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2467888 | pubmed:dateCreated | 1989-5-15 | lld:pubmed |
| pubmed-article:2467888 | pubmed:abstractText | A conjugate of mitomycin C and the mannan of bakers' yeast (Saccharomyces cerevisiae wild type strain) was synthesized. Assay of its growth inhibitory effect on MH134 hepatoma solid tumor implanted in C3H/He slc mice showed that this conjugate exhibited a higher growth-inhibition ratio than those of free mitomycin C and the same bakers' yeast mannan in the corresponding effective doses. This conjugate was also found to kill the same hepatoma cells in vitro. Because a dextran-mitomycin C conjugate did not manifest any antitumor effect against this tumor, it was postulated that interaction of the mannan moiety in the mannan-mitomycin C conjugate with the mannose receptor located on the cell surface of immunocytes and/or with hepatoma cells participated in the common initiating reaction of in vitro and in vivo antitumor effects. | lld:pubmed |
| pubmed-article:2467888 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2467888 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2467888 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2467888 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2467888 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2467888 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2467888 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2467888 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2467888 | pubmed:issn | 0192-0561 | lld:pubmed |
| pubmed-article:2467888 | pubmed:author | pubmed-author:TsukadaKK | lld:pubmed |
| pubmed-article:2467888 | pubmed:author | pubmed-author:SuzukiSS | lld:pubmed |
| pubmed-article:2467888 | pubmed:author | pubmed-author:MatsumotoTT | lld:pubmed |
| pubmed-article:2467888 | pubmed:author | pubmed-author:ItoAA | lld:pubmed |
| pubmed-article:2467888 | pubmed:author | pubmed-author:SatoHH | lld:pubmed |
| pubmed-article:2467888 | pubmed:author | pubmed-author:SuzukiMM | lld:pubmed |
| pubmed-article:2467888 | pubmed:author | pubmed-author:AizawaKK | lld:pubmed |
| pubmed-article:2467888 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2467888 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:2467888 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2467888 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2467888 | pubmed:pagination | 191-5 | lld:pubmed |
| pubmed-article:2467888 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:meshHeading | pubmed-meshheading:2467888-... | lld:pubmed |
| pubmed-article:2467888 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2467888 | pubmed:articleTitle | Antitumor effect of a baker's yeast mannan-mitomycin C conjugate against mouse hepatoma, MH134, in vivo and in vitro. | lld:pubmed |
| pubmed-article:2467888 | pubmed:affiliation | Department of Microbiology, Tohoku College of Pharmacy, Miyagi, Japan. | lld:pubmed |
| pubmed-article:2467888 | pubmed:publicationType | Journal Article | lld:pubmed |
