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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1989-5-3
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pubmed:abstractText |
The immunohistological classification of 97 pituitary adenomas revealed in 34 cases alpha-subunit (a-su) positive cells in the tumor tissue. In 15 cases a-su was the only hormone found, in 11 cases the beta-subunits of the glycoprotein hormones could also be detected (10 cases with LH/FSH and 1 case with TSH). In 8 cases a-su was found simultaneously together with other hormones of the pituitary (ACTH and a-su in 1 case, GH and a-su in 4 cases, prolactin and a-su in 2 cases, prolactin, GH and a-su in 1 case). A-su could be demonstrated to be partly simultaneously produced together with these hormones in identical cells and secretory granules. Next to prolactin, the a-su was the second most frequently occurring hormone that could be detected immunohistologically in our material.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0344-0338
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
183
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
601-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2467268-Adenoma,
pubmed-meshheading:2467268-Adult,
pubmed-meshheading:2467268-Aged,
pubmed-meshheading:2467268-Female,
pubmed-meshheading:2467268-Glycoprotein Hormones, alpha Subunit,
pubmed-meshheading:2467268-Humans,
pubmed-meshheading:2467268-Immune Sera,
pubmed-meshheading:2467268-Immunohistochemistry,
pubmed-meshheading:2467268-Male,
pubmed-meshheading:2467268-Middle Aged,
pubmed-meshheading:2467268-Pituitary Hormones, Anterior,
pubmed-meshheading:2467268-Pituitary Neoplasms
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pubmed:year |
1988
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pubmed:articleTitle |
Simultaneous production of the alpha-subunit of glycoprotein hormones and other hormones in pituitary adenomas.
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pubmed:affiliation |
Universitätsklinikum R. Virchow, Institut für Pathologie, Berlin West, West Germany.
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pubmed:publicationType |
Journal Article
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