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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1978-6-12
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pubmed:abstractText |
The most prominent symptom of Shy-Drager syndrome is the asympathicotonic orthostatic (postural) hypotension, which is associated with a number of additional autonomic and neurological disturbances: disorders of micturition, sphincter disturbances, impotence, anhidrosis, hypokinesia, rigidity, pyramidal symptoms, cerebellar dysfunction and nuclear pareses due to anterior horn cell degeneration. The various disorders are not caused by ischemia or hypotension, but they represent parts of a multisystemic disease of still unknown etiology. According to different extension and neuropathological criteria it has been suggested to distinguish two types of neurogenic (idiopathic) orthostatic hypotension. Moreover, differential diagnosis of the Shy-Drager syndrome has to consider postural hypotension occuring as a symptom in some neuropathies and Parkinson's disease. Symptomatology, course, prognosis and treatment of Shy-Drager syndrome are described, as well as relevant findings of apparative investigations, pharmacological and hemodynamic tests and neuropathological findings in autopsied cases reported in the literature. This review was initiated by two clinically investigated cases of Shy-Drager syndrome.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0015-8194
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-43
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:246413-Adult,
pubmed-meshheading:246413-Autonomic Nervous System,
pubmed-meshheading:246413-Brain,
pubmed-meshheading:246413-Electroencephalography,
pubmed-meshheading:246413-Fecal Incontinence,
pubmed-meshheading:246413-Fludrocortisone,
pubmed-meshheading:246413-Humans,
pubmed-meshheading:246413-Hypotension, Orthostatic,
pubmed-meshheading:246413-Male,
pubmed-meshheading:246413-Middle Aged,
pubmed-meshheading:246413-Nervous System Diseases,
pubmed-meshheading:246413-Paralysis,
pubmed-meshheading:246413-Prognosis,
pubmed-meshheading:246413-Syndrome,
pubmed-meshheading:246413-Urinary Incontinence
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pubmed:year |
1978
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pubmed:articleTitle |
[The Shy-Drager syndrome (author's transl)].
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|