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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1988-12-12
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pubmed:abstractText |
A standardized hyperventilation (HV) procedure has been developed in which the end-tidal pCO2 was decreased to 2 kpa. In 24 young male subjects blood flow velocity and qEEG were studied before, during and after HV. This standardized hyperventilation procedure gave rise to a decrease in blood flow velocity to 40% of baseline value and highly significant qEEG changes in 3 derivations. Both relative and absolute band power estimates showed an increase in slow activity and a decrease in alpha and beta activity. The use of subtraction spectra led to a more precise and detailed presentation of these changes than the use of classical qEEG parameters. These changes were reproducible after 1 week. The effects found in the presented model of HV-induced ischaemia appeared to be twice as large as those found in a model of hypobaric hypoxia. The present model might be used to test the efficacy of anti-ischaemic drugs in young human subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0013-4694
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
377-87
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pubmed:dateRevised |
2008-9-9
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pubmed:meshHeading |
pubmed-meshheading:2460311-Adult,
pubmed-meshheading:2460311-Blood Flow Velocity,
pubmed-meshheading:2460311-Brain,
pubmed-meshheading:2460311-Brain Ischemia,
pubmed-meshheading:2460311-Electroencephalography,
pubmed-meshheading:2460311-Humans,
pubmed-meshheading:2460311-Hyperventilation,
pubmed-meshheading:2460311-Hypoxia, Brain,
pubmed-meshheading:2460311-Male
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pubmed:year |
1988
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pubmed:articleTitle |
Changes in quantitative EEG and blood flow velocity due to standardized hyperventilation; a model of transient ischaemia in young human subjects.
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pubmed:affiliation |
Dept. of Clinical Neurophysiology, University Hospital Utrecht, The Netherlands.
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pubmed:publicationType |
Journal Article
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